Evaluation of the S-Caine Peel for Induction of Local Anesthesia for Laser-Assisted Tattoo Removal: Randomized, Double-Blind, Placebo-Controlled, Multicenter Study

Evaluation of the S-Caine Peel for Induction of Local Anesthesia for Laser-Assisted Tattoo Removal: Randomized, Double-Blind, Placebo-Controlled, Multicenter Study
March 2005
# Chen John Z.S., MD**Division of Dermatology, University of Louisville, Louisville, Kentucky,
# Jacobson Laurie G., MD‹‹Laser and Skin Surgery Center of New York, New York, New York,
# Bakus Aboneal D., PhD··Department of Biomedical Engineering, Northwestern University, Chicago, Illinois,
# Garden Jerome M., MD··Department of Biomedical Engineering, Northwestern University, Chicago, Illinois??Department of Dermatology, Northwestern University, Chicago, Illinois,
# Yaghmai Dina, MD??Department of Dermatology, Northwestern University, Chicago, Illinois,
# Bernstein Leonard J., MD‹‹Laser and Skin Surgery Center of New York, New York, New York AND
# Geronemus Roy G., MD
Dermatologic Surgery

BackgroundTopical anesthetics are important tools for many dermatologic procedures. The S-Caine Peel is composed of a 1:1 (w:w) eutectic mixture composed of lidocaine base 7%, USP, and tetracaine base 7%, USP. It is applied as a cream, dries on exposure to air, and forms a flexible membrane, which can be easily peeled off.
ObjectiveTo evaluate the effectiveness of the S-Caine Peel in providing clinically useful local dermal anesthesia for laser-assisted tattoo removal and to monitor the nature and frequency of adverse events associated with the safety of the S-Caine Peel.

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