Laser-Assisted Tattoo Removal with Topical 5% Imiquimod Cream

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Laser-Assisted Tattoo Removal with Topical 5% Imiquimod Cream
September 2007
# CARLOS A. RICOTTI, MD**Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida; ,
# SHANTHI M. COLACO, BA++University of California at San Francisco School of Medicine, San Francisco, California; ,
# H. NICHOLAS SHAMMA, MD?Dermatopathology Laboratory of Central States, ?Wright State University School of Medicine, Dayton, Ohio; ,
# JULIAN TREVINO, MD??Wright State University School of Medicine, Dayton, Ohio; ,
# GARY PALMER, MD?||?Wright State University School of Medicine, Dayton, Ohio; ||Dermatology and Laser Surgery Center, Centerville, Ohio, AND
# MICHAEL R. HEAPHY JR, MD
Dermatologic Surgery

BACKGROUND Laser-assisted tattoo removal is effective but can be costly and time-consuming and can result in disfiguring scars and pigment alterations. Imiquimod, an immune response modifier, may play a role in tattoo removal.
OBJECTIVE The objective was to evaluate the safety and efficacy of topical 5% imiquimod cream used daily in conjunction with laser therapy to remove unwanted tattoos.

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