Review of Modern Techniques in Detecting Port-wine Stain Response to Laser Therapy

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Review of Modern Techniques in Detecting Port-wine Stain Response to Laser Therapy
February 1999
To cite this article: Khanh-Van T. Le MD, Hossain Shahidullah MD, Ilona J. Frieden MD (1999)
Review of Modern Techniques in Detecting Port-wine Stain Response to Laser Therapy
Dermatologic Surgery 25 (2), 127Ò132.
doi:10.1046/j.1524-4725.1999.08166.x

Khanh-Van T. Le MD, Hossain Shahidullah MD & Ilona J. Frieden MD
1Department of Dermatology, University of California, San Francisco, San Francisco, California
Correspondence to: Ilona J. Frieden MD , 400 Parnassus Avenue, Box 0316, A-309, San Francisco, CA 94143-0316.

Abstract
Background. Traditional mechanisms of assessing port-wine stain response to laser therapy have rested mainly on subjective determinations by physician and patient. However, the wide variation in treatment response poses a profound need for objective devices to measure treatment outcomes so that maximum effectiveness of therapy can be achieved without unnecessary repeat treatments.

Objective. The purpose of this paper will be to review noninvasive techniques to measure port-wine stain response to laser therapy.

Methods. This report is based on a review of medical and bioscience literature.

Results. Several techniques including laser Doppler, reflectance spectrophotometry, tristimulus colorimetry, and videomicroscopy have been developed to address the need for objective measurement devices.

Conclusion. While many instruments are available, these techniques are limited by cost, small test size area, and/or inconclusive correlation with clinical response. A number of experimental techniques may circumvent many of the problems inherent in currently-available commercial technologies.

This article is cited by:
A. Yung and R. Sheehan-Dare. (2005) A comparative study of a 595-nm with a 585-nm pulsed dye laser in refractory port wine stains. British Journal of Dermatology 153:3, 601Ò606
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Etsuo Chosa, Tomohisa Sekimoto, Shinichiro Kubo, Naoya Tajima. (2005) Evaluation of Circulatory Compromise in the Leg in Lumbar Spinal Canal Stenosis. Clinical Orthopaedics and Related Research :431, 129
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Byungjo Jung, Chang-Seok Kim, Bernard Choi, Kristen M. Kelly, J. Stuart Nelson. (2005) Use of erythema index imaging for systematic analysis of port wine stain skin response to laser therapy. Lasers in Surgery and Medicine 37:3, 186
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Henry H. Chan, David S. Y. Wong, W. S. Ho, L. K. Lam, and W. Wei. (2004) The Use of Pulsed Dye Laser for the Prevention and Treatment of Hypertrophic Scars in Chinese Persons. Dermatologic Surgery 30:7, 987Ò994
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Byungjo Jung, Bernard Choi, Anthony J. Durkin, Kristen M. Kelly, J. Stuart Nelson. (2004) Characterization of port wine stain skin erythema and melanin content using cross-polarized diffuse reflectance imaging. Lasers in Surgery and Medicine 34:2, 174
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Vivek Sivarajan, Iain R. Mackay. (2004) The depth measuring videomicroscope (DMV): A non-invasive tool for the assessment of capillary vascular malformations. Lasers in Surgery and Medicine 34:2, 193
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Chun-Hung Chiu, MPhil, Henry Hin-Lee Chan, FRCP, Wai-Sun Ho, FRCS, Chi-Keung Yeung, MRCP, and J. Stuart Nelson, MD, PhD. (2003) Prospective Study of Pulsed Dye Laser in Conjunction With Cryogen Spray Cooling for Treatment of Port Wine Stains in Chinese Patients. Dermatologic Surgery 29:9, 909Ò915
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Simon A Yong-Gee, Habib A Kurwa and Richard J Barlow. (2001) Objective assessment of port-wine stains following treatment with the 585 nm pulsed dye laser. Australasian Journal of Dermatology 42:4, 243Ò246
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Dong Kyun Rah, Soo Chan Kim, Kwang Hoon Lee, Beyoung Yun Park, Deok Won Kim. (2001) Objective Evaluation of Treatment Effects on Port-Wine Stains Using L*a*b* Color Coordinates. Plastic and Reconstructive Surgery 108:4, 842
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