Subbasal Nerve Regeneration After LASEK Measured by Confocal Microscopy

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Subbasal Nerve Regeneration After LASEK Measured by Confocal Microscopy
September 2007
Taym Darwish, PhD, MSc; Arun Brahma, MD; Nathan Efron, PhD, DSc; Clare ÒDonnell, PhD, MCOptom, FAAO
Journal of Refractive Surgery Vol. 23 No. 7

PURPOSE
To determine the relationship between the degree of subbasal nerve regeneration and corneal sensation and tear film functions after LASEK using corneal confocal microscopy.

METHODS
This prospective, observational, and longitudinal study included 35 LASEK patients who underwent tear breakup time assessment, phenol red thread test, corneal esthesiometry, and confocal microscopy preoperatively and 1, 3, and 6 months postoperatively. Subbasal nerve images were analyzed to assess nerve regeneration.

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