The Use of Variable Pulse Width Frequency Doubled Nd:YAG 532 nm Laser in the Treatment of Port-Wine Stain in Chinese Patients

The Use of Variable Pulse Width Frequency Doubled Nd:YAG 532 nm Laser in the Treatment of Port-Wine Stain in Chinese Patients
July 2000
To cite this article: Henry H. Chan FRCP (Glas), Edmond Chan FRCS, Taro Kono MD, Shun-Yuen Ying FRCS, Wai-Sun Ho, FRCS (2000)
The Use of Variable Pulse Width Frequency Doubled Nd:YAG 532 nm Laser in the Treatment of Port-Wine Stain in Chinese Patients
Dermatologic Surgery 26 (7), 657Ò661.
doi:10.1046/j.1524-4725.2000.00014.x

Henry H. Chan, FRCP (Glas),**Division of Dermatology, Department of Medicine, University of Hong Kong, Hong King, Edmond Chan, FRCS,Department of Plastic and Reconstructive Surgery, Prince of Wales Hospital, Hong Kong, and Taro Kono, MD,Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Tokyo, Japan Shun-Yuen Ying, FRCS,Department of Plastic and Reconstructive Surgery, Prince of Wales Hospital, Hong Kong, and and Wai-Sun Ho, FRCS
Department of Plastic and Reconstructive Surgery, Prince of Wales Hospital, Hong Kong, and *Division of Dermatology, Department of Medicine, University of Hong Kong, Hong King, Department of Plastic and Reconstructive Surgery, Prince of Wales Hospital, Hong Kong, and Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Tokyo, Japan
H. Chan, FRCP (Glas), E. Chan, FRCS, T. Kono, MD, S.-Y. Ying, FRCS, and W.-S. Ho, FRCS have indicated no significant interest with commercial supporters.

Address correspondence and reprint requests to: Henry H.L. Chan, FRCP, Division of Dermatology, Department of Medicine, 4F, Professorial Block, Queen Mary Hospital, Honk Kong, or e-mail: hhlchan@hkucc.hku.hk.

Abstract
Background. Variable pulse width frequency doubled Nd:YAG 532 nm laser has previously been shown to be effective in the treatment of vascular lesions in Caucasians. For dark-skinned patients, such as Asians, its role has not been determined.

Objective. To assess the clinical efficacy and complication rate of the 532 nm Nd:YAG laser in the treatment of port-wine stain in Chinese patients.

Methods. Chinese patients with port-wine stain who had undergone Nd:YAG laser treatment were called for questionnaire assessment of their degree of clearing and clinical examination for complications by two independent observers. For 22 patients with pre- and posttreatment photographs, the two independent observers further assessed the degree of clearing.

Results. Assessment of the questionnaire indicated that 62.9% of the patients subjectively considered that they had more than 25% clearing, with 33.3% having more than 50% clearing. For those with pre- and posttreatment photographs, the objective degree of improvement was less impressive with 18.1% of patients having at least 25% improvement and only 13.6% having more than 50% improvement. Pigmentary and texture changes were seen in both groups (33% in group I and 11% in group II). The number of treatment sessions rather than previous use of pulsed dye laser therapy was an important risk factor for complications.

Conclusion. Nd:YAG laser is only partially effective for the treatment of port-wine stain in Chinese patients. Although most patients recorded some degree of subjective improvement, many did not improve by objective assessment. High fluence is necessary to achieve the desirable clinical response, and while contact cooling reduces the risk of epidermal damage, texture changes can still occur. Further study is necessary to compare its use with other similar devices, such as a pulsed dye laser with cryogen spray cooling.

This article is cited by:
S.W. Lanigan and S.M. Taibjee. (2004) Recent advances in laser treatment of port-wine stains. British Journal of Dermatology 151:3, 527Ò533
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Wai Sun Ho, FRCS, Shun Yuen Ying, FRCS, Pik Chu Chan, RN, and Henry H. Chan, MD, FRCP. (2004) Treatment of Port Wine Stains with Intense Pulsed Light: A Prospective Study. Dermatologic Surgery 30:6, 887Ò891
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Henry H. Chan, FRCP, Murad Alam, MD, Taro Kono, MD, and Jeffery S. Dover, MD, FRCPC. (2002) Clinical Application of Lasers in Asians. Dermatologic Surgery 28:7, 556Ò563
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Wai Sun Ho, Henry H Chan, Shun Yuen Ying, Pik Chu Chan. (2002) Laser treatment of congenital facial port-wine stains: Long-term efficacy and complication in Chinese patients. Lasers in Surgery and Medicine 30:1, 44
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